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Search Results for " fas ligand "

1

抑制剂 & 化合物

1

天然产物

9

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T80584	Anti-Mouse Fas Ligand Antibody (MFL3)
	Anti-Mouse Fas Ligand Antibody为针对小鼠Fas Ligand的IgG类抗体抑制剂，由Armenian Hamster产生。

化合物

Anti-Mouse Fas Ligand Antibody (MFL3)

Cat.No: T80584

Cat. No.	Product Name	Target	Signaling Pathways
T13815	Penicillic acid	Apoptosis; Caspase; Antibacterial; Antibiotic	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Penicillic acid，一种由多种Aspergillus和Penicillium物种合成的polyketide mycotoxin，通过阻碍caspase-8的自我处理作用，抑制Fas ligand引发的apoptosis。此外，体外研究表明，Penicillic acid在rat alveolar macrophages中显示出cytotoxic特性。

天然产物

Penicillic acid

Cat.No: T13815

Target: Apoptosis, Caspase, Antibacterial, Antibiotic

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His) TNLG1A,FASL,FASLG,CD178,CD95-L,APT1LG1,APT...	Human	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei...
TMPY-04913	Fas Ligand Protein, Rat, Recombinant (His) Fas ligand	Rat	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei...
TMPY-04587	Fas Ligand Protein, Mouse, Recombinant (His) CD178,Apt1lg1,Fasl,Cd95l,Faslg,Tnfsf6,gld,...	Mouse	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei...
TMPY-03435	NCKIPSD Protein, Human, Recombinant (GST) NCK interacting protein with SH3 domain,WASLBP,SPIN90,ORF1,V...	Human	E. coli
	NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an important role in stress fiber formation. NCKIPSD gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding d...
TMPK-01378	IL-12B Protein, Cynomolgus, Recombinant (His) CLMF2,NKSF2,CLMF,CLMF p40,IL-12B,IL-12 subunit p40,NKS	Cynomolgus	HEK293 Cells
	Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studi...
TMPH-02590	COL4A2 Protein, Mouse, Recombinant (His) COL4A2,Collagen alpha-2(IV) chain	Mouse	E. coli
	Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptos...
TMPY-01824	Caspase-14 Protein, Human, Recombinant (His) caspase 14, apoptosis-related cysteine peptidase,ARCI12	Human	E. coli
	Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Casp...
TMPY-02597	IL-37 Protein, Human, Recombinant FIL1Z,IL-37,白细胞介素,IL37,IL1F7,IL-1RP1,FIL1(ζ),IL1RP1,FIL1,白介素...	Human	E. coli
	Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases, and/or cancer. Through constructing an adenoviral vector that allows high-level expression i...
TMPY-02578	DKKL1 Protein, Human, Recombinant (hFc) SGY,dickkopf-like 1,CT34,SGY1,SGY-1	Human	HEK293 Cells
	Dickkopf-like 1 (DKKL1) or soggy 1, is a glycoprotein unique to mammals that is expressed primarily in developing spermatocytes and localized in the acrosome of mature sperm. It is also expressed in the trophectoderm / placental lineage. This glycoprotein is secreted by postmeiotic male germ cells. DKKL1 is a member of the Dickkopf (DKK) family, a group of proteins that are characterized as secreted antagonists of Wnt signal transduction proteins. In mammals, embryos lacking DKKL1 protein develo...

重组蛋白

Fas Ligand Protein, Human, Recombinant (His)

Cat.No: TMPY-03956

Species: Human

Expression System: P. pastoris (Yeast)

Fas Ligand Protein, Rat, Recombinant (His)

Cat.No: TMPY-04913

Species: Rat

Expression System: P. pastoris (Yeast)

Fas Ligand Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04587

Species: Mouse

Expression System: P. pastoris (Yeast)

NCKIPSD Protein, Human, Recombinant (GST)

Cat.No: TMPY-03435

Species: Human

Expression System: E. coli

IL-12B Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01378

Species: Cynomolgus

Expression System: HEK293 Cells

COL4A2 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02590

Species: Mouse

Expression System: E. coli

Caspase-14 Protein, Human, Recombinant (His)

Cat.No: TMPY-01824

Species: Human

Expression System: E. coli

IL-37 Protein, Human, Recombinant

Cat.No: TMPY-02597

Species: Human

Expression System: E. coli

DKKL1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02578

Species: Human

Expression System: HEK293 Cells

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